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Gabriel Ferri, Lucía R. Fernández, Guillermo Di Mario, Jorge A. Palermo and Martin M. Edreira
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From Benznidazole to New Drugs: Nanotechnology Contribution in Chagas Disease

Daniele Cavalcante Gomes, Thayse Silva Medeiros, Eron Lincoln Alves Pereira, João Felipe Oliveira da Silva, Johny W. de Freitas Oliveira, Matheus de Freitas Fernandes-Pedrosa, Marcelo de Sousa da Silva and Arnóbio Antônio da Silva-Júnior
International Journal of Molecular Sciences 24 (18) 13778 (2023)
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A mathematical model for Chagas disease transmission with neighboring villages

Daniel J. Coffield, Anna Maria Spagnuolo, Ryan Capouellez and Gabrielle A. Stryker
Frontiers in Applied Mathematics and Statistics 9 (2023)
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Comparative microRNA profiling of Trypanosoma cruzi infected human cells

Natalia Rego, María Gabriela Libisch, Carlos Rovira, Juan Pablo Tosar and Carlos Robello
Frontiers in Cellular and Infection Microbiology 13 (2023)
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Targeting Metalloenzymes: The “Achilles’ Heel” of Viruses and Parasites

Dimitrios Moianos, Georgia-Myrto Prifti, Maria Makri and Grigoris Zoidis
Pharmaceuticals 16 (6) 901 (2023)
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Development of 3D-QSAR and pharmacophoric models to design new anti-Trypanosoma cruzi agents based on 2-aryloxynaphthoquinone scaffold

M. Paulino, C. Espinosa-Bustos, J. Bertrand, et al.
SAR and QSAR in Environmental Research 33 (9) 701 (2022)
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Contextual influence on poor self-rated health in patients with Chagas disease: multilevel study

Ariela Mota Ferreira, Ester Cerdeira Sabino, Léa Campos de Oliveira-da Silva, et al.
Ciência & Saúde Coletiva 27 (7) 2827 (2022)
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Climate change and the prevention of cardiovascular disease

Alan P. Jacobsen, Yii Chun Khiew, Eamon Duffy, et al.
American Journal of Preventive Cardiology 12 100391 (2022)
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Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019

Sunny Wei, J Jamie Miranda, Mamas A Mamas, et al.
European Heart Journal - Quality of Care and Clinical Outcomes (2022)
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Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate

Samuel L. Freeman, Vera Skafar, Hanna Kwon, et al.
Journal of Biological Chemistry 298 (8) 102204 (2022)
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Frequency of Human Papillomavirus Detection in Chagasic Megaesophagus Associated or Not with Esophageal Squamous Cell Carcinoma

Fernanda Franco Munari, Laura Sichero, Adriana Cruvinel Carloni, et al.
Pathobiology 89 (1) 29 (2022)
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New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase

Christian Espinosa-Bustos, Mariana Ortiz Pérez, Alonzo Gonzalez-Gonzalez, et al.
Pharmaceutics 14 (6) 1121 (2022)
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Impact of IFN-γ Deficiency on the Cardiomyocyte Function in the First Stage of Experimental Chagas Disease

Danilo Roman-Campos, Policarpo Sales-Junior, Alexandre D. Costa, et al.
Microorganisms 10 (2) 271 (2022)
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Amazon Rainforest: A Natural Source for New Therapeutic Alternatives against Neglected Tropical Diseases

Soraya da Silva Santos, João Vitor Silva, Pone Kamdem Boniface and Jeanine Giarolla
The Natural Products Journal 12 (6) (2022)
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Editorial: Signaling in stress sensing and resistance in parasitic protozoa

Arijit Bhattacharya, Christopher Fernandez-Prada, Guillermo Daniel Alonso and Arunima Biswas
Frontiers in Cellular and Infection Microbiology 12 (2022)
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Chagas Disease Ecology in the United States: Recent Advances in Understanding Trypanosoma cruzi Transmission Among Triatomines, Wildlife, and Domestic Animals and a Quantitative Synthesis of Vector–Host Interactions

Rachel E. Busselman and Sarah A. Hamer
Annual Review of Animal Biosciences 10 (1) 325 (2022)
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Antikinetoplastid Activity of Sesquiterpenes Isolated from the Zoanthid Palythoa aff. clavata

Carlos J. Bethencourt-Estrella, Nathalia Nocchi, Atteneri López-Arencibia, et al.
Pharmaceuticals 14 (11) 1095 (2021)
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In vitro studies and preclinical evaluation of benznidazole microparticles in the acute Trypanosoma cruzi murine model

Marcela S. Rial, Katia P. Seremeta, Mónica I. Esteva, et al.
Parasitology 148 (5) 566 (2021)
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Diaminomaleonitrile derivatives as new potential antichagasic compounds: a study of structure–activity relationships

Aldo S de Oliveira, Lucas dos S Mello, Camila H Ogihara, et al.
Future Medicinal Chemistry 13 (24) 2167 (2021)
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New benzimidazolequinones as trypanosomicidal agents

Claudia López-Lira, Ricardo A. Tapia, Alejandra Herrera, et al.
Bioorganic Chemistry 111 104823 (2021)
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Immunomodulation and Antioxidant Activities as Possible Trypanocidal and Cardioprotective Mechanisms of Major Terpenes from Lippia alba Essential Oils in an Experimental Model of Chronic Chagas Disease

Denerieth Ximena Espinel-Mesa, Clara Isabel González Rugeles, Julio César Mantilla Hernández, et al.
Antioxidants 10 (11) 1851 (2021)
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Cohort profile update: the main and new findings from the SaMi-Trop Chagas cohort

Claudia Di Lorenzo Oliveira, Clareci Silva Cardoso, Nayara Ragi Baldoni, et al.
Revista do Instituto de Medicina Tropical de São Paulo 63 (2021)
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A Rapid Review on the Efficacy and Safety of Pharmacological Treatments for Chagas Disease

Cody J Malone, Immaculate Nevis, Eduardo Fernández and Ana Sanchez
Tropical Medicine and Infectious Disease 6 (3) 128 (2021)
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Ficolin‐3 in chronic Chagas disease: Low serum levels associated with the risk of cardiac insufficiency

Kárita Cláudia Freitas Lidani, Fabiana Antunes Andrade, Marcia Holsbach Beltrame, Indira Chakravarti, Maria Regina Tizzot, Edneia Oliveira Cavalcanti, Thaisa Lucas Sandri, Paola Rosa Luz and Iara J. Messias‐Reason
Parasite Immunology 43 (6) (2021)
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Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents

Francisco Salgado, Mauricio Moncada-Basualto, Josue Pozo-Martinez, et al.
Arabian Journal of Chemistry 14 (3) 102975 (2021)
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Searching for drugs for Chagas disease, leishmaniasis and schistosomiasis: a review

Soraya Silva Santos, Renan Vinicius de Araújo, Jeanine Giarolla, Omar El Seoud and Elizabeth Igne Ferreira
International Journal of Antimicrobial Agents 55 (4) 105906 (2020)
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Recent Progress in the Discovery and Development of 2-Nitroimidazooxazines and 6-Nitroimidazooxazoles to Treat Tuberculosis and Neglected Tropical Diseases

Hollis D. Showalter
Molecules 25 (18) 4137 (2020)
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Factors associated with quality of life in patients with Chagas disease: SaMi-Trop project

Nayara Dornela Quintino, Ester Cerdeira Sabino, José Luiz Padilha da Silva, et al.
PLOS Neglected Tropical Diseases 14 (5) e0008144 (2020)
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A Fluorinated Phenylbenzothiazole Arrests the Trypanosoma cruzi Cell Cycle and Diminishes the Infection of Mammalian Host Cells

Roberto I. Cuevas-Hernández, Richard M. B. M. Girard, Sarai Martínez-Cerón, et al.
Antimicrobial Agents and Chemotherapy 64 (2) (2020)
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Zeinab Ghasemi, Shadi Banitaan and Ghaith Al-Refai
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Foregut Surgery

Leonardo M. Del Grande and Fernando A. M. Herbella
Foregut Surgery 23 (2020)
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Benznidazole as Prophylaxis for Chagas Disease Infection Reactivation in Heart Transplant Patients: A Case Series in Brazil

Joao Manoel Rossi Neto, Marco Aurelio Finger and Carolina Casadei dos Santos
Tropical Medicine and Infectious Disease 5 (3) 132 (2020)
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Risk Score for Predicting 2‐Year Mortality in Patients With Chagas Cardiomyopathy From Endemic Areas: SaMi‐Trop Cohort Study

Claudia Di Lorenzo Oliveira, Maria Carmo P. Nunes, Enrico Antonio Colosimo, et al.
Journal of the American Heart Association 9 (6) (2020)
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Factors associated with Chagas screening among immigrants from an endemic country in Madrid, Spain

María Romay-Barja, Teresa Boquete, Obdulia Martinez, et al.
PLOS ONE 15 (3) e0230120 (2020)
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Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection

Gurdip Singh Mann, Amanda F. Francisco, Shiromani Jayawardhana, et al.
PLOS Neglected Tropical Diseases 14 (4) e0007717 (2020)
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Mixed infections by different Trypanosoma cruzi discrete typing units among Chagas disease patients in an endemic community in Panama

Alexa Prescilla Ledezma, Roberto Blandon, Alejandro G. Schijman, et al.
PLOS ONE 15 (11) e0241921 (2020)
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Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy

Andrew M. Thompson, Patrick D. O’Connor, Andrew J. Marshall, et al.
European Journal of Medicinal Chemistry 207 112849 (2020)
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Performance Evaluation of a Commercial Real-Time PCR Assay and of an In-House Real-Time PCR for Trypanosoma cruzi DNA Detection in a Tropical Medicine Reference Center, Northern Italy

Silvia Stefania Longoni, Elena Pomari, Alberto Antonelli, et al.
Microorganisms 8 (11) 1692 (2020)
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MicroRNAs: Biological Regulators in Pathogen–Host Interactions

Stephanie Maia Acuña, Lucile Maria Floeter-Winter and Sandra Marcia Muxel
Cells 9 (1) 113 (2020)
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A Trypanosoma cruzi Genome Tandem Repetitive Satellite DNA Sequence as a Molecular Marker for a LAMP Assay for Diagnosing Chagas’ Disease

Diego Ordóñez, Pedro Fernández-Soto, Ana M. Fernández-Martín, et al.
Disease Markers 2020 1 (2020)
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Diversity and genome mapping assessment of disordered and functional domains in trypanosomatids

Grace Santos Tavares Avelar, Leilane Oliveira Gonçalves, Frederico Gonçalves Guimarães, et al.
Journal of Proteomics 227 103919 (2020)
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Role of FAK signaling in chagasic cardiac hypertrophy

Amanda R. Tucci, Francisco O. R. de Oliveira, Guilherme C. Lechuga, et al.
The Brazilian Journal of Infectious Diseases 24 (5) 386 (2020)
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Elucidating diversity in the class composition of the minicircle hypervariable region of Trypanosoma cruzi: New perspectives on typing and kDNA inheritance

Fanny Rusman, Nicolás Tomasini, Noelia-Floridia Yapur, et al.
PLOS Neglected Tropical Diseases 13 (6) e0007536 (2019)
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Chagas Disease: From Discovery to a Worldwide Health Problem

Kárita Cláudia Freitas Lidani, Fabiana Antunes Andrade, Lorena Bavia, et al.
Frontiers in Public Health 7 (2019)
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A reduction in ecological niche for Trypanosoma cruzi-infected triatomine bugs

Guiehdani Villalobos, Angela Nava-Bolaños, José A. De Fuentes-Vicente, et al.
Parasites & Vectors 12 (1) (2019)
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Increased frequencies of circulating CCR5+ memory T cells are correlated to chronic chagasic cardiomyopathy progression

Ester Roffe, Luara I Dos Santos, Maykon O Santos, et al.
Journal of Leukocyte Biology 106 (3) 641 (2019)
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Potential Utility of Protein Targets of Cysteine-S-Nitrosylation in Identifying Clinical Disease Status in Human Chagas Disease

Maria Paola Zago, John E. Wiktorowicz, Heidi Spratt, et al.
Frontiers in Microbiology 9 (2019)
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A Combination of Itraconazole and Amiodarone Is Highly Effective against Trypanosoma cruzi Infection of Human Stem Cell–Derived Cardiomyocytes

Gabriele Sass, Roy T. Madigan, Lydia-Marie Joubert, et al.
The American Journal of Tropical Medicine and Hygiene 101 (2) 383 (2019)
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Glucocorticoids and sympathetic neurotransmitters modulate the acute immune response to Trypanosoma cruzi

Eduardo Roggero, Adriana del Rey, Johannes Wildmann and Hugo Besedovsky
Annals of the New York Academy of Sciences 1437 (1) 83 (2019)
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Chagas Disease Treatment and Rational Drug Discovery: A Challenge That Remains

Ana Catarina Cristovão Silva, Maria Carolina Accioly Brelaz-de-Castro, Ana Cristina Lima Leite, Valéria Rêgo Alves Pereira and Marcelo Zaldini Hernandes
Frontiers in Pharmacology 10 (2019)
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Inhibition of C. albicans Dimorphic Switch by Cobalt(II) Complexes with Ligands Derived from Pyrazoles and Dinitrobenzoate: Synthesis, Characterization and Biological Activity

Daniela Fonseca, Sandra M. Leal-Pinto, Martha V. Roa-Cordero, et al.
International Journal of Molecular Sciences 20 (13) 3237 (2019)
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Trypanosoma cruzi immunoproteome: Calpain-like CAP5.5 differentially detected throughout distinct stages of human Chagas disease cardiomyopathy

Marcelle A. Caminha, Virginia Maria B. de Lorena, Wilson de Oliveira Júnior, et al.
Journal of Proteomics 194 179 (2019)
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Community-based surveillance and control of chagas disease vectors in remote rural areas of the Argentine Chaco: A five-year follow-up

María C. Cecere, Lucía I. Rodríguez-Planes, Gonzalo M. Vazquez-Prokopec, Uriel Kitron and Ricardo E. Gürtler
Acta Tropica 191 108 (2019)
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Advances in understanding the role of adipose tissue and mitochondrial oxidative stress in Trypanosoma cruzi infection

Jyothi F. Nagajyothi and Louis M. Weiss
F1000Research 8 1152 (2019)
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Parasitic Diseases Within the Spinal Cord and Nerve Roots

Benjamin Rahmani, Shrey Patel, Omar Seyam, et al.
SN Comprehensive Clinical Medicine 1 (11) 869 (2019)
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The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole

Carlos Robello, Doris Patricia Maldonado, Anna Hevia, et al.
PLOS ONE 14 (2) e0212593 (2019)
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Chagas disease as example of a reemerging parasite

Jeannette Guarner
Seminars in Diagnostic Pathology 36 (3) 164 (2019)
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Gurdip Singh Mann, Amanda F. Francisco, Shiromani Jayawardhana, Martin C. Taylor, Michael D. Lewis, Francisco Olmo, Elisangela Oliveira de Freitas, Fabiana M. S. Leoratti, Cesar López-Camacho, Arturo Reyes-Sandoval and John M. Kelly
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Jenny Yeon Hee Kim, Julia Ledien, Eliana Rodriguez-Monguí, Andy Dobson, María-Gloria Basáñez and Zulma M. Cucunubá
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Are the London Declaration’s 2020 goals sufficient to control Chagas disease?: Modeling scenarios for the Yucatan Peninsula

Bruce Y. Lee, Sarah M. Bartsch, Laura Skrip, et al.
PLOS Neglected Tropical Diseases 12 (3) e0006337 (2018)
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Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis

Lyda Z. Rojas, Marija Glisic, Laura Pletsch-Borba, et al.
PLOS Neglected Tropical Diseases 12 (6) e0006567 (2018)
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Benefits of Ascorbic Acid in Association with Low-Dose Benznidazole in Treatment of Chagas Disease

Maiara Voltarelli Providello, Zumira Aparecida Carneiro, Gisele Bulhões Portapilla, et al.
Antimicrobial Agents and Chemotherapy 62 (9) (2018)
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Foodborne Parasites

Charles R. Sterling
Foodborne Parasites 17 (2018)
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Molecular description of α‐keto‐based inhibitors of cruzain with activity against Chagas disease combining 3D‐QSAR studies and molecular dynamics

Ádria P. B. Saraiva, Ricardo M. Miranda, Renan P. P. Valente, Jéssica O. Araújo, Rutelene N. B. Souza, Clauber H. S. Costa, Amanda R. S. Oliveira, Michell O. Almeida, Antonio F. Figueiredo, João E. V. Ferreira, Cláudio Nahum Alves and Kathia M. Honorio
Chemical Biology & Drug Design 92 (2) 1475 (2018)
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Solid Organ Transplant and Parasitic Diseases: A Review of the Clinical Cases in the Last Two Decades

Silvia Fabiani, Simona Fortunato and Fabrizio Bruschi
Pathogens 7 (3) 65 (2018)
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The Trypanosoma cruzi RNA-binding protein RBP42 is expressed in the cytoplasm throughout the life cycle of the parasite

R. Tyler Weisbarth, Anish Das, Paul Castellano, et al.
Parasitology Research 117 (4) 1095 (2018)
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Pyrazinoates as antiparasitic agents against Trypanosoma cruzi

Camilla I. Vasconcelos, Marina T. Varela, Ana C. Torrecilhas and João P. S. Fernandes
Archiv der Pharmazie 351 (11) (2018)
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2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas’ disease

Michael G. Thomas, Manu De Rycker, Ignacio Cotillo Torrejon, et al.
Bioorganic & Medicinal Chemistry Letters 28 (18) 3025 (2018)
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Early Trypanosoma cruzi Infection Triggers mTORC1-Mediated Respiration Increase and Mitochondrial Biogenesis in Human Primary Cardiomyocytes

M. Gabriela Libisch, Paula Faral-Tello, Nisha J. Garg, et al.
Frontiers in Microbiology 9 (2018)
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Lysosomes - Associated Diseases and Methods to Study Their Function

Barbara Hissa and Luciana O. Andrade
Lysosomes - Associated Diseases and Methods to Study Their Function (2017)
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6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases

Andrew M. Thompson, Adrian Blaser, Brian D. Palmer, Robert F. Anderson, Sujata S. Shinde, Delphine Launay, Eric Chatelain, Louis Maes, Scott G. Franzblau, Baojie Wan, Yuehong Wang, Zhenkun Ma and William A. Denny
Bioorganic & Medicinal Chemistry Letters 27 (11) 2583 (2017)
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Trans-sialidase overcomes many antigens to be used as a vaccine candidate against Trypanosoma cruzi

Ivan Bontempi, Pedro Fleitas, Alexia Poato, et al.
Immunotherapy 9 (7) 555 (2017)
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Chagas Disease Infection among Migrants at the Mexico/Guatemala Border

Erin E. Conners, Carmen Fernández Casanueva, Sonia Morales Miranda, et al.
The American Journal of Tropical Medicine and Hygiene 97 (4) 1134 (2017)
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Kinetics, subcellular localization, and contribution to parasite virulence of a Trypanosoma cruzi hybrid type A heme peroxidase ( Tc APx-CcP)

Martín Hugo, Alejandra Martínez, Madia Trujillo, et al.
Proceedings of the National Academy of Sciences 114 (8) (2017)
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Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

Christopher A. Seid, Kathryn M. Jones, Jeroen Pollet, et al.
Human Vaccines & Immunotherapeutics 13 (3) 621 (2017)
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Antitrypanosomal activity and evaluation of the mechanism of action of dehydrodieugenol isolated from Nectandra leucantha (Lauraceae) and its methylated derivative against Trypanosoma cruzi

Simone S. Grecco, Thais A. Costa-Silva, Gerold Jerz, et al.
Phytomedicine 24 62 (2017)
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The Complement System: A Prey of Trypanosoma cruzi

Kárita C. F. Lidani, Lorena Bavia, Altair R. Ambrosio and Iara J. de Messias-Reason
Frontiers in Microbiology 8 (2017)
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Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens

Simona John Von Freyend, Terry Kwok-Schuelein, Hans Netter, et al.
Pathogens 6 (2) 17 (2017)
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Benznidazole treatment safety: the Médecins Sans Frontières experience in a large cohort of Bolivian patients with Chagas' disease

Gilberto Marcelo Sperandio da Silva, Mauro Felippe Felix Mediano, Alejandro Marcel Hasslocher-Moreno, et al.
Journal of Antimicrobial Chemotherapy 72 (9) 2596 (2017)
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Sylvatic host associations of Triatominae and implications for Chagas disease reservoirs: a review and new host records based on archival specimens

Anna Y. Georgieva, Eric R.L. Gordon and Christiane Weirauch
PeerJ 5 e3826 (2017)
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Diet regulates liver autophagy differentially in murine acute Trypanosoma cruzi infection

Kezia Lizardo, Vanessa Almonte, Calvin Law, et al.
Parasitology Research 116 (2) 711 (2017)
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Eco-social processes influencing infectious disease emergence and spread

BRYONY A. JONES, MARTHA BETSON and DIRK U. PFEIFFER
Parasitology 144 (1) 26 (2017)
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Comparison of four PCR methods for efficient detection of Trypanosoma cruzi in routine diagnostics

Peter Seiringer, Michael Pritsch, María Flores-Chavez, et al.
Diagnostic Microbiology and Infectious Disease 88 (3) 225 (2017)
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Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differences and similarities between the parasite and host

Vitor Sueth-Santiago, Debora Decote-Ricardo, Alexandre Morrot, Celio Geraldo Freire-de-Lima and Marco Edilson Freire Lima
World Journal of Biological Chemistry 8 (1) 57 (2017)
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Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

Stephen Brand, Eun Jung Ko, Elisabet Viayna, et al.
Journal of Medicinal Chemistry 60 (17) 7284 (2017)
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Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors

Nir Qvit, Deborah Schechtman, Darlene Aparecida Pena, et al.
International Journal for Parasitology: Drugs and Drug Resistance 6 (1) 74 (2016)
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Success of benznidazole chemotherapy in chronic Trypanosoma cruzi-infected patients with a sustained negative PCR result

L. Murcia, B. Carrilero, F. Ferrer, et al.
European Journal of Clinical Microbiology & Infectious Diseases 35 (11) 1819 (2016)
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An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells

Richard M. B. M. Girard, Marcell Crispim, Ivana Stolić, et al.
Antimicrobial Agents and Chemotherapy 60 (10) 5867 (2016)
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Status of vaccine research and development of vaccines for Chagas disease

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