On the importance of targeting parasite stem cells in anti-echinococcosis drug development
Parasite, 21 (2014) 72
Published online: 2014-12-22
Articles citing this article
The Citing articles tool gives a list of articles citing the current article.
The citing articles come from EDP Sciences database, as well as other publishers participating in CrossRef Cited-by Linking Program. You can set up your personal account to receive an email alert each time this article is cited by a new article (see the menu on the right-hand side of the abstract page).
Cited article:
This article has been cited by the following article(s):
Human Alveolar Echinococcosis—A Neglected Zoonotic Disease Requiring Urgent Attention
Ali Rostami, Britta Lundström-Stadelmann, Caroline F. Frey, Guido Beldi, Anja Lachenmayer, Bill C. H. Chang, Mohammad Mobin Norouzian, Andrew Hemphill and Robin B. GasserInternational Journal of Molecular Sciences 26 (6) 2784 (2025)
https://doi.org/10.3390/ijms26062784
Combined fluorescent in situ hybridization and F-ara-EdU staining on whole mount Hymenolepis diminuta
Mohamed Ishan, Isabell R Skipper and Tania RozarioBiology Methods and Protocols 10 (1) (2025)
https://doi.org/10.1093/biomethods/bpaf011
Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model
Zhuo-ma Dawa, Ting Zhai, Chuan-chuan Liu and Hai-ning FanFrontiers in Medicine 12 (2025)
https://doi.org/10.3389/fmed.2025.1503472
Investigation of the threonine metabolism of Echinococcus multilocularis: The threonine dehydrogenase as a potential drug target in alveolar echinococcosis
Marc Kaethner, Pascal Zumstein, Joachim Müller, Matías Preza, Philipp Grossenbacher, Anissa Bartetzko, Laura Vetter, Martin Lochner, Stefan Schürch, Clement Regnault, Daniel Villalobos Ramírez and Britta Lundström-StadelmannInternational Journal for Parasitology: Drugs and Drug Resistance 27 100581 (2025)
https://doi.org/10.1016/j.ijpddr.2025.100581
Synthetic rEg.P29 Peptides Induce Protective Immune Responses Against Echinococcus granulosus in Mice
Yongxue Lv, Jing Tang, Tao Li, Yinqi Zhao, Changyou Wu and Wei ZhaoVaccines 13 (3) 266 (2025)
https://doi.org/10.3390/vaccines13030266
Host Proteins in Echinococcus multilocularis Metacestodes
Joachim Müller, Beatrice Zumkehr, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache and Britta Lundström-StadelmannInternational Journal of Molecular Sciences 26 (7) 3266 (2025)
https://doi.org/10.3390/ijms26073266
Efficacy and Safety of Asparagusic Acid against Echinococcus multilocularis In Vitro and in a Murine Infection Model
Zhuanhong Lu, Yating Wang, Chuanchuan Liu and Haining FanTropical Medicine and Infectious Disease 9 (5) 110 (2024)
https://doi.org/10.3390/tropicalmed9050110
Genome-wide transcriptome analysis of Echinococcus multilocularis larvae and germinative cell cultures reveals genes involved in parasite stem cell function
Michaela Herz, Magdalena Zarowiecki, Leonie Wessels, Katharina Pätzel, Ruth Herrmann, Christiane Braun, Nancy Holroyd, Thomas Huckvale, Monika Bergmann, Markus Spiliotis, Uriel Koziol, Matthew Berriman and Klaus BrehmFrontiers in Cellular and Infection Microbiology 14 (2024)
https://doi.org/10.3389/fcimb.2024.1335946
Receptor Tyrosine Kinase Signaling Involves Echinococcus–Host Intercommunication: A Potential Therapeutic Target in Hepatic Echinococcosis
Haijun Gao, Zhuoma Bianba, Xiaojin Mo, Wei Hu, Zheng Feng, Fangye Zhou and Ting ZhangTropical Medicine and Infectious Disease 9 (8) 175 (2024)
https://doi.org/10.3390/tropicalmed9080175
(2024)
https://doi.org/10.1101/2024.07.27.605433
19 219 (2024)
https://doi.org/10.1007/978-3-031-54479-8_13
Effect of Hydroxyurea on Morphology, Proliferation, and Protein Expression on Taenia crassiceps WFU Strain
Diana G. Rios-Valencia, Karel Estrada, Arturo Calderón-Gallegos, Rocío Tirado-Mendoza, Raúl J. Bobes, Juan P. Laclette and Margarita Cabrera-BravoInternational Journal of Molecular Sciences 25 (11) 6061 (2024)
https://doi.org/10.3390/ijms25116061
Treatment of uncomplicated hepatic cystic echinococcosis (hydatid disease)
Rebecca Kuehn, Leonardo J Uchiumi and Francesca TamarozziCochrane Database of Systematic Reviews 2024 (7) (2024)
https://doi.org/10.1002/14651858.CD015573
(2024)
https://doi.org/10.21203/rs.3.rs-5020183/v1
(2024)
https://doi.org/10.1101/2024.12.20.629808
Echinococcus multilocularis delta/notch signalling components are expressed in post-mitotic cells
Chris Speicher, Monika Bergmann and Klaus BrehmParasitology Research 123 (12) (2024)
https://doi.org/10.1007/s00436-024-08442-4
In Vitro Activities of Dithiocarbamate Derivatives against Echinococcus multilocularis Metacestode Vesicles
Marc Kaethner, Georg Rennar, Tom Gallinger, Tobias Kämpfer, Andrew Hemphill, Patrick Mäder, Ana Luque-Gómez, Martin Schlitzer and Britta Lundström-StadelmannTropical Medicine and Infectious Disease 8 (12) 517 (2023)
https://doi.org/10.3390/tropicalmed8120517
Watch-and-wait approach for inactive echinococcal cysts: scoping review update since the issue of the WHO-IWGE Expert Consensus and current perspectives
Enrico Brunetti and Francesca TamarozziCurrent Opinion in Infectious Diseases 36 (5) 326 (2023)
https://doi.org/10.1097/QCO.0000000000000943
Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus sensu stricto
Marc Kaethner, Matías Preza, Tobias Kaempfer, Pascal Zumstein, Claudia Tamponi, Antonio Varcasia, Andrew Hemphill, Klaus Brehm, Britta Lundström-Stadelmann and Cristian A. Alvarez RojasPLOS Neglected Tropical Diseases 17 (8) e0011343 (2023)
https://doi.org/10.1371/journal.pntd.0011343
Establishment of a secondary infection laboratory model of Echinococcus shiquicus metacestode using BALB/c mice and Mongolian jirds (Meriones unguiculatus)
Yantao Wu, Li Li, Fuling Xu, Hongbin Yan, John Asekhaen Ohiolei, Nigus Abebe Shumuye, Xiaofeng Nian, Wenhui Li, Nianzhang Zhang, Baoquan Fu and Wanzhong JiaParasitology 1 (2023)
https://doi.org/10.1017/S0031182023000604
The combination of carvacrol and albendazole enhanced the efficacy of monotherapy in experimental alveolar echinococcosis
Lurdes Milagros Lopez, Patricia Eugenia Pensel, Julia Fabbri, et al.Acta Tropica 225 106198 (2022)
https://doi.org/10.1016/j.actatropica.2021.106198
Cellular and molecular basis associated with metacestode proliferation in subarachnoid neurocysticercosis
Miguel A. Orrego, Manuela R. Verastegui and Hector H. GarciaFrontiers in Immunology 13 (2022)
https://doi.org/10.3389/fimmu.2022.1025599
Targeting Echinococcus multilocularis PIM kinase for improving anti-parasitic chemotherapy
Akito Koike, Frank Becker, Peter Sennhenn, et al.PLOS Neglected Tropical Diseases 16 (10) e0010483 (2022)
https://doi.org/10.1371/journal.pntd.0010483
Transcriptional effects of electroporation on Echinococcus multilocularis primary cell culture
Matías Gastón Pérez, Natalia Rego, Markus Spiliotis, Klaus Brehm and Mara Cecilia RosenzvitParasitology Research 121 (4) 1155 (2022)
https://doi.org/10.1007/s00436-022-07427-5
Emerging Model Systems in Developmental Biology
Tania Rozario, James J. Collins and Phillip A. NewmarkCurrent Topics in Developmental Biology, Emerging Model Systems in Developmental Biology 147 345 (2022)
https://doi.org/10.1016/bs.ctdb.2021.12.015
Expression profiling of Echinococcus multilocularis miRNAs throughout metacestode development in vitro
Natalia Macchiaroli, Matías Preza, Matías Gastón Pérez, et al.PLOS Neglected Tropical Diseases 15 (3) e0009297 (2021)
https://doi.org/10.1371/journal.pntd.0009297
PET/CT helps to determine treatment duration in patients with resected as well as inoperable alveolar echinococcosis
Lars Husmann, Urs J. Muehlematter, Felix Grimm, et al.Parasitology International 83 102356 (2021)
https://doi.org/10.1016/j.parint.2021.102356
Echinococcus granulosus sensu lato and Echinococcus multilocularis: A review
Ian David Woolsey and Andrea L. MillerResearch in Veterinary Science 135 517 (2021)
https://doi.org/10.1016/j.rvsc.2020.11.010
A case for adoption of continuous albendazole treatment regimen for human echinococcal infections
Francesca Tamarozzi, John Horton, Marin Muhtarov, et al.PLOS Neglected Tropical Diseases 14 (9) e0008566 (2020)
https://doi.org/10.1371/journal.pntd.0008566
In Vitro and In Vivo Efficacies of the EGFR/MEK/ERK Signaling Inhibitors in the Treatment of Alveolar Echinococcosis
Zhe Cheng, Zhijian Xu, Huimin Tian, et al.Antimicrobial Agents and Chemotherapy 64 (8) (2020)
https://doi.org/10.1128/AAC.00341-20
Metformin Suppresses Development of the Echinococcus multilocularis Larval Stage by Targeting the TOR Pathway
Julia A. Loos, Valeria A. Dávila, Klaus Brehm and Andrea C. CuminoAntimicrobial Agents and Chemotherapy 64 (9) (2020)
https://doi.org/10.1128/AAC.01808-19
Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis
Britta Lundström-Stadelmann, Reto Rufener and Andrew HemphillInternational Journal for Parasitology: Drugs and Drug Resistance 13 121 (2020)
https://doi.org/10.1016/j.ijpddr.2020.06.002
Albendazole solid dispersions against alveolar echinococcosis: a pharmacotechnical strategy to improve the efficacy of the drug
Julia Fabbri, Patricia Eugenia Pensel, Clara María Albani, et al.Parasitology 147 (9) 1026 (2020)
https://doi.org/10.1017/S0031182020000670
Activity of Thymus capitatus essential oil components against in vitro cultured Echinococcus multilocularis metacestodes and germinal layer cells
Amani Hizem, Britta Lundström-Stadelmann, Selim M'rad, et al.Parasitology 146 (07) 956 (2019)
https://doi.org/10.1017/S0031182019000295
The importance of being parasiticidal… an update on drug development for the treatment of alveolar echinococcosis
Britta Lundström-Stadelmann, Reto Rufener, Dominic Ritler, Raphael Zurbriggen and Andrew HemphillFood and Waterborne Parasitology 15 e00040 (2019)
https://doi.org/10.1016/j.fawpar.2019.e00040
253 (2019)
https://doi.org/10.1002/9783527808656.ch10
Region-specific regulation of stem cell-driven regeneration in tapeworms
Tania Rozario, Edward B Quinn, Jianbin Wang, Richard E Davis and Phillip A NewmarkeLife 8 (2019)
https://doi.org/10.7554/eLife.48958
Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro
Matías Gastón Pérez, Markus Spiliotis, Natalia Rego, et al.PLOS Neglected Tropical Diseases 13 (12) e0007932 (2019)
https://doi.org/10.1371/journal.pntd.0007932
Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase
Zhe Cheng, Fan Liu, Huimin Tian, et al.PLOS Neglected Tropical Diseases 13 (5) e0007425 (2019)
https://doi.org/10.1371/journal.pntd.0007425
Recombinant α- and β-tubulin from Echinococcus granulosus: expression, purification and polymerization
Congshan Liu, Jiaqing Yao, Jianhai Yin, Jian Xue and Haobing ZhangParasite 25 62 (2018)
https://doi.org/10.1051/parasite/2018063
Recurrent Multi-Organ Cystic Echinococcosis
Adriana Habor, Noémi Ecaterina Sidlovszky, Edina Török, Iunius Simu, Monica Copotoiu and Larisa MureșanInternal Medicine 15 (2) 59 (2018)
https://doi.org/10.2478/inmed-2018-0015
Progress in the pharmacological treatment of human cystic and alveolar echinococcosis: Compounds and therapeutic targets
Mar Siles-Lucas, Adriano Casulli, Roberto Cirilli, David Carmena and Giovanna RasoPLOS Neglected Tropical Diseases 12 (4) e0006422 (2018)
https://doi.org/10.1371/journal.pntd.0006422
Genome-wide transcriptome profiling and spatial expression analyses identify signals and switches of development in tapeworms
Peter D. Olson, Magdalena Zarowiecki, Katherine James, et al.EvoDevo 9 (1) (2018)
https://doi.org/10.1186/s13227-018-0110-5
(2018)
https://doi.org/10.1101/495234
96 259 (2017)
https://doi.org/10.1016/bs.apar.2016.09.006
EGF-mediated EGFR/ERK signaling pathway promotes germinative cell proliferation in Echinococcus multilocularis that contributes to larval growth and development
Zhe Cheng, Fan Liu, Xiu Li, et al.PLOS Neglected Tropical Diseases 11 (2) e0005418 (2017)
https://doi.org/10.1371/journal.pntd.0005418
95 147 (2017)
https://doi.org/10.1016/bs.apar.2016.09.001
95 65 (2017)
https://doi.org/10.1016/bs.apar.2016.07.001
96 1 (2017)
https://doi.org/10.1016/bs.apar.2016.09.005
Update on Treatment for Cystic Echinococcosis of the Liver
Enrico Brunetti, Liliana Praticò, Andreas Neumayr, Marcello Maestri and Francesca TamarozziCurrent Treatment Options in Infectious Diseases 8 (3) 153 (2016)
https://doi.org/10.1007/s40506-016-0079-3
Current interventional strategy for the treatment of hepatic alveolar echinococcosis
Dominique A. Vuitton, Amel Azizi, Carine Richou, et al.Expert Review of Anti-infective Therapy 14 (12) 1179 (2016)
https://doi.org/10.1080/14787210.2016.1240030
Efficacy of osthole for Echinococcus granulosus in vitro and Echinococcus multilocularis in vivo
Miaomiao Yuan, Yanping Luo, Qi Xin, et al.Veterinary Parasitology 226 38 (2016)
https://doi.org/10.1016/j.vetpar.2016.05.016
Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis
Britta Stadelmann, Reto Rufener, Denise Aeschbacher, et al.PLOS Neglected Tropical Diseases 10 (3) e0004535 (2016)
https://doi.org/10.1371/journal.pntd.0004535
Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin
Tatiana Küster, Britta Stadelmann, Reto Rufener, et al.International Journal of Antimicrobial Agents 46 (5) 546 (2015)
https://doi.org/10.1016/j.ijantimicag.2015.07.016
Prevention and Immunotherapy of Secondary Murine Alveolar Echinococcosis Employing Recombinant EmP29 Antigen
Ghalia Boubaker, Andrew Hemphill, Cristina Olivia Huber, et al.PLOS Neglected Tropical Diseases 9 (6) e0003795 (2015)
https://doi.org/10.1371/journal.pntd.0003795