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Supplementary Figure 3:
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Mapping of estimated guide RNA (gRNA) sequences to the hypervariable region (mHVR) of T. lainsoni minicircles. The number of estimated gRNAs mapped to each base position in the mHVR is shown. The distribution indicates that the estimated positions of gRNAs range from approximately 77 bp to 202 bp downstream of CSB-3.
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