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Figure 2

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Regulatory effects of exosomes on immune functions of sheep PBMCs. (A) qPCR analysis of the expression of the core components in the LPS/TLR4 pathway after treatment with exosomes. (B) qPCR analysis of the expression of cytokines after treatment with exosomes. (C) The level of NO after treatment with exosomes determined by Griess reagent. (D) qPCR analysis of the expression of the iNOS after treatment with exosomes. Data are expressed as mean ± SD; *p < 0.05. Data for the final analysis are from three independent experiments. NC, negative control.

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