Therapeutic efficacy and safety of artesunate + amodiaquine and artemether + lumefantrine in treating uncomplicated Plasmodium falciparum malaria in children on the rainy south-east coast of Madagascar

Open Access

Table 6

Efficacy of first-line antimalarial drugs at day 28 stratified by site, age and study arm, Madagascar 2018.

	Study arm
Per protocol				Kaplan–Meier
ASAQ		AL		ASAQ		AL
%	95%CI	%	95%CI	%	95%IC	%	95%IC
Region
Antsenavolo	100	87.2–100	100	86.7–100	100	87.2–100	100	87.2–100
Kianjavato	100	93.7–100	94.9	89.5–100	100	94–100	95.1	89.9–100
Vohitromby	100	95.9–100	98.8	96.6–100	100	95.9–100	98.8	86.6–100
Age (years old)
0.5–4	100	93.2–100	96.2	91.2–100	100	93.2–100	96.2	91.2–100
5–14	100	63–100	98.3	96–100	100	63–100	98.4	96.1–100
Gender
Female	100	95.9–100	97.7	94.6–100	100	95.9–100	97.7	94.7–100
Male	100	95.7–100	97.6	94.4–100	100	95.7–100	97.7	94.7–100

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