Open Access
Table 2
IgG titers, IB-recomLine sensitivity, specificity and overall agreement between IB-recomLine and other assays.
| Serum group (number of sera) | ELISA mean IgG levels ± SD (IU/mL) |
IB-recomLine sensitivity (%) [95% CI] |
IB-recomLine specificity (%) [95% CI] |
IgG overall agreement (%) (kappa value) between IB-recomLine and other assays | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ARCHITECT | VIDAS | Equivocal IB results = negative | Equivocal IB results = positive | Equivocal IB results = negative | Equivocal IB results = positive | ARCHITECT | VIDAS | WB-LDBIO | ||
| Negative | <1.6 | <4 | ||||||||
| Equivocal | [1.6–2.9] | [4–7] | ||||||||
| Positive | ≥3 | ≥8 | ||||||||
| 1 (n = 50) | 51.4 ± 112.1 | 95.1 ± 102.9 | 97.1 [84.7–99.9] | 100 [89.7–100] | 100 [79.4–100] | 93.8 [69.8–99.8] | 94 (0.87) | 90 (0.8) | NP | |
| 2 (n = 47) | 2.9 ± 3.5 | 6.7 ± 2.8 | 58.1 [39.1–75.5] | 77.4 [58.9–90.4] | 87.5 [61.7–98.5] | 50 [24.7–75.4] | NP | NP | 55.3 (0.27) | |
SD: standard deviation; CI: confidence interval; NP: not performed
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