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Table 2
Specificity of individual HAT diagnostic tests and test combinations, performed in parallel or in series.
| Diagnostic test | Total positive | % specificity (95% CI) | test negative/HAT freea |
|---|---|---|---|
| rHAT Sero-Strip | 42 | 99.3 (99.0–99.5) | 5828/5870 |
| SD-Bioline HAT | 419 | 92.9 (92.2–93.5) | 5451/5870 |
| HAT Sero-K-Set | 641 | 89.1 (88.3–89.8) | 5229/5870 |
| All RDTs (in parallel) | 829 | 85.9 (85.0–86.7) | 5041/5870 |
| Sero-K-Set + rHAT Sero-Strip (parallel) | 666 | 88.7 (87.8–89.4) | 5204/5870 |
| HAT Sero-K-Set + SD Bioline (parallel) | 807 | 86.3 (85.4–87.1) | 5063/5870 |
| rHAT Sero Strip + SD Bioline HAT (parallel) | 453 | 92.3 (91.6–92.9) | 5417/5870 |
| All RDTs (in series) | 5 | 99.9 (99.8–100) | 5865/5870 |
| Sero-K-Set + rHAT Sero-Strip (series) | 17 | 99.7 (99.5–99.8) | 5853/5870 |
| HAT Sero-K-Set + SD Bioline (series) | 253 | 95.7 (95.1–96.2) | 5617/5870 |
| rHAT Sero Strip + SD Bioline HAT (series) | 8 | 99.9 (99.7–99.9) | 5862/5870 |
| Trypanolysis | 0 | 100 (99.5–100) | 816/816 |
| ELISA/T. b. gambiense | 7 | 99.1 (98.5–99.7) | 809/816 |
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