Efficacy of a novel topical combination of esafoxolaner, eprinomectin and praziquantel in cats against Toxocara cati and Dipylidium caninum

Special Issue – NexGard^® Combo (esafoxolaner, eprinomectin, praziquantel): A new endectocide spot-on formulation for cats. Invited Editor: Frédéric Beugnet

Open Access

Table 1

Study-specific information: animal details, allocation, and target parasites.

	Study 1	Study 2	Study 3	Study 4	Study 5
Target parasite (origin)	Toxocara cati (Tennessee, USA)	Toxocara cati (Albania)	Dipylidium caninum (South Africa)	Dipylidium caninum (Albania)	Dipylidium caninum (Mexico)
Infection	Induced	Natural	Induced	Natural	Natural
Age of cats, range	19–21 weeks	5–8 months	1–9 years	2–4 years	3 months to 3 years
Bodyweight of cats, range (kg)	2.0–2.9	1.0–2.1	2.5–4.6	1.2–3.6	1.3–5.0
Number of cats per group	10	10	8	10	10
Allocation of cats to treatment groups	Completely at random	At random after blocking by bodyweight	At random after blocking by bodyweight	At random after blocking by bodyweight	At random after blocking by bodyweight
Timing of parasite recovery after treatment	7 days	7/8 days	7 days	10/11 days	10–12 days

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