Table 4
Ctenocephalides felis adulticide efficacy.
| n cats | Arithmetic means (AM) of live fleas and % efficacy on indicated days | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Study #1 | Day 1 | Day 7 | Day 14 | Day 21 | Day 28 | Day 35 | Day 42 | Day 49 | Day 56 | ||
| Control group | 9 | AM | 74.2 | 74.0 | 82.2 | 69.3 | 57.6 | 66.9 | 63.7 | 60.4 | 69.4 |
| Treated group | 9 | AM | 0.2 | 0.0 | 0.0 | 0.0 | 0.1 | 0.2 | 0.2 | 1.9 | 7.9 |
| % efficacy | 99.7 | 100.0 | 100.0 | 100.0 | 99.8 | 99.7 | 99.7 | 96.9 | 88.6 | ||
| Study #2 | Day 1 | Day 8 | Day 15 | Day 22 | Day 31 | – | – | – | – | ||
| Control group | 10 | AM | 68.2 | 74.7 | 68.8 | 77.2 | 73.0 | – | – | – | – |
| Treated group | 10 | AM | 5.4 | 0.1 | 0.0 | 0.4 | 3.3 | – | – | – | – |
| % efficacy | 92.1 | 99.9 | 100.0 | 99.5 | 95.5 | – | – | – | – | ||
| Study #4 | Day 1 | Day 7 | Day 14 | Day 21 | Day 31 | Day 38 | – | – | – | ||
| Control group | 10 | AM | 64.5 | 69.6 | 69.5 | 72.1 | 62.4 | 49.2 | – | – | – |
| Treated group | 10 | AM | 1.1 | 0.0 | 0.3 | 0.3 | 0.7 | 4.8 | – | – | – |
| % efficacy | 98.3 | 100.0 | 99.6 | 99.6 | 98.9 | 90.2 | – | – | – | ||
Note: p-values for comparison of the untreated and treated groups were <0.0001 at all timepoints.
The percent efficacy was calculated as [(C − T)/C] × 100, where C was the arithmetic mean of the flea counts among the placebo control cats, and T was the arithmetic mean among the Nexgard® Combo-treated cats.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.