Table 1
Study objectives and contexts.
| Objective(s) | Location/date | C. felis strain origin | Variable used for randomization | Variable(s) of efficacy | |
|---|---|---|---|---|---|
| Study #1 | Adulticide efficacy for 8 weeks | France/Jan–Mar 2018 | Germany | Pre-treatment adult flea count 24 h | 24-h weekly flea reduction |
| Study #2 | Adulticide efficacy and egg production for 1 month | USA (CA)/Aug–Sep 2017 | California | Pre-treatment adult flea count 24 h | 24-h weekly flea reduction; egg production and larval hatching reduction |
| Study #3 | Inhibition of egg production for 1 month | South Africa/Oct–Nov 2017 | Hungary | Pre-treatment larval hatching | Egg production and larval hatching reduction |
| Study #4 | Adulticide efficacy for 5 weeks | South Africa/Nov–Dec 2019 | Germany | Pre-treatment adult flea count 24 h | 24-h weekly flea reduction |
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