|Field trial||Objective(s)||Location||Date||Positive control||Ratio IVP/PCP||Primary variables of efficacy|
|USA||Flea efficacy & safety for 3 months, reduction of flea infestation-related cutaneous signs||Southeast, Midwest, Western USA||Apr 2017 – Nov 2018||Selamectin||2/1||Flea reduction at 1 month for sentinel cats|
|EU||Flea efficacy & safety for 1 month, reduction of flea infestation-related cutaneous signs||Western, Central, Eastern Europe||Apr 2017 – Oct 2017||Fipronil, (S)-methoprene||2/1||Weekly flea reduction for sentinel cats for 1 month, non-inferiority versus positive control|
|Japan||Flea efficacy & safety for 1 month||6 prefectures in Kanto, Chubu and Kyushu||Jul 2017 – Jan 2018||Selamectin||1/1||Flea reduction at 2 days and 1 month (all cats), non-inferiority versus positive control|
|Australia||Flea efficacy & safety for 1 month||NSW, QLD||Jan 2019 – Mar 2019||NA||NA||Flea reduction at 1 month for sentinel cats|
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