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Table 2

Characteristics of the eight patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.

Characteristic Result
Demographic characteristics
 Age (years) 24.3 [0.87–63.6]
 Sex (male) 6 (75%)
 Rainy season 6 (75%)
 Exposure risk
  Reported contact with snails 2 (25%)
  Previous mental disorders 5 (63%)
Clinical picture
 Fever (>38 °C) 5 (63%)
 Digestive signs and symptoms 3 (38%)
 Neurological signs and symptoms 8 (100%)
  Headaches 2 (25%)
  Neck stiffness 1 (13%)
  Dysfunction of cranial nerves 3 (38%)
  Seizure 2 (25%)
  Axial hypotonia, hemiparesia 2 (25%)
  Radiculalgia 1 (13%)
  Coma 2 (25%)
Brain imaging
 Normal 3 (38%)
 Enlargement of cerebral ventricles 3 (38%)
 Cortical atrophy 1 (13%)
Laboratory results
 In blood
  C-reactive protein > 5 mg/L 2 (25%)
  Total WBC count (G/L) 10.0 [6.61–20.75]
  Blood eosinophilia at admission (G/L) 1.72 [0.49–6.43]
  Blood eosinophilia at admission (% of WBC) 12.5 [5–31]
  Max blood eosinophilia during hospitalisation (G/L) 2.99 [0.89–6.43]
  Max blood eosinophilia during hospitalisation (% of WBC) 23.5 [10–36]
  A. cantonensis positive serodiagnosis 7 (88%)
 In CSF
  Eosinophilia in CSF at first LP (/mm3) 74.5 [0–1550]
  Eosinophilia in CSF at first LP (% of WBC) 25.0 [0–68]
  CSF glucose at first LP (mmol/L) 2.81 [0.1–4.3]
  Protein level in CSF at first LP (g/L) 1.14 [0.33–1.71]
  Protein level > 0.45 g/L at first LP 7 (88%)
  Presence of antibodies in CSF (among those tested) 6 (100%)
Management
 Length of hospital stay (days) 27 [15–66]
 Subtractive LP 5 (63%)
 Corticosteroids 5 (63%)
 Anthelmintic therapy 7 (88%)
Outcome
 One year recovery 2 (25%)
 One year neurological sequelae 5 (63%)
 One year mortality 1 (13%)

Abbreviations: CSF, cerebrospinal fluid; LP, lumbar puncture; WBC, white blood cell.

Descriptive results are presented as n (%) and as median (min–max).

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