Characteristics of the eight patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.
|Age (years)||24.3 [0.87–63.6]|
|Sex (male)||6 (75%)|
|Rainy season||6 (75%)|
|Reported contact with snails||2 (25%)|
|Previous mental disorders||5 (63%)|
|Fever (>38 °C)||5 (63%)|
|Digestive signs and symptoms||3 (38%)|
|Neurological signs and symptoms||8 (100%)|
|Neck stiffness||1 (13%)|
|Dysfunction of cranial nerves||3 (38%)|
|Axial hypotonia, hemiparesia||2 (25%)|
|Enlargement of cerebral ventricles||3 (38%)|
|Cortical atrophy||1 (13%)|
|C-reactive protein > 5 mg/L||2 (25%)|
|Total WBC count (G/L)||10.0 [6.61–20.75]|
|Blood eosinophilia at admission (G/L)||1.72 [0.49–6.43]|
|Blood eosinophilia at admission (% of WBC)||12.5 [5–31]|
|Max blood eosinophilia during hospitalisation (G/L)||2.99 [0.89–6.43]|
|Max blood eosinophilia during hospitalisation (% of WBC)||23.5 [10–36]|
|A. cantonensis positive serodiagnosis||7 (88%)|
|Eosinophilia in CSF at first LP (/mm3)||74.5 [0–1550]|
|Eosinophilia in CSF at first LP (% of WBC)||25.0 [0–68]|
|CSF glucose at first LP (mmol/L)||2.81 [0.1–4.3]|
|Protein level in CSF at first LP (g/L)||1.14 [0.33–1.71]|
|Protein level > 0.45 g/L at first LP||7 (88%)|
|Presence of antibodies in CSF (among those tested)||6 (100%)|
|Length of hospital stay (days)||27 [15–66]|
|Subtractive LP||5 (63%)|
|Anthelmintic therapy||7 (88%)|
|One year recovery||2 (25%)|
|One year neurological sequelae||5 (63%)|
|One year mortality||1 (13%)|
Abbreviations: CSF, cerebrospinal fluid; LP, lumbar puncture; WBC, white blood cell.
Descriptive results are presented as n (%) and as median (min–max).
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