Mean pharmacokinetic (PK) parameters in the two groups of animals treated with IVM.
|PK parameters||Value||Treatment group
|500 mg (1.5–2 mg/kg)||1000 mg (3–4 mg/kg)|
|AUC0–tlast (ng day/mL)||Mean||1239||3116|
Cmax = maximum observed plasma concentration; Tmax = time of maximum observed plasma concentration; Clast = last measurable concentration (above the quantification limit); AUC0–tlast = area under the concentration-time curve to the last measurable concentration; SD = standard deviation; CV = coefficient of variation.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.