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Table 3.

Myocardial histopathological abnormalities found in mice during the acute phase of T. cruzi experimental infection (60 days post-infection)

Parameters/group G1 G2 G3 G4 G5 G6 G7 G8
Focal lymphoplasmacytes ++ + +
Diffuse lymphoplasmacytes +
Cardiomyocyte necrosis + ++ + +
Amastigote nests (mean ± SD) 35 ± (3.9) 24 ± (3.05) 0 0 0 0 0 0

Treatment groups: G1: T. cruzi; G2: T. cruzi/ASTX; G3: T. cruzi/ASTX/NFMX; G4: T. cruzi/NFMX; G5: saline solution; G6: NFMX; G7: ASTX/NFMX; G8: ASTX. Abnormality scale: −, none; +, light; ++, moderate; and +++, severe [5]; ±: standard deviation.

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