Table 2.
Detailed chronological histopathological results in the glomeruli.
| Phenomenon observed |
||||
|---|---|---|---|---|
| Groups | Time (D.p.i.) | Obliterated capillaries | Mesangial cells proliferation | Macrophages with pigment |
| N | 13 | 0 | 0 | 0 |
| 30 | 0 | 0 | 0 | |
| P. y | 13 | 3/3 | 3/3 | 3/3 |
| 14 | 20 | 72 | ||
| 30 | 0 | 3/3 | 0 | |
| 18 | ||||
| P. c | 13 | 0 | 0 | 0 |
| 30 | 3/6 | 6/6 | 0 | |
| 12 | 20 | |||
| P.y + L. s | 13 | 1/3 | 3/3 | 3/3 |
| 9 | 12 | 54 | ||
| 30 | 0 | 1/3 | 0 | |
| 6 | ||||
| P. c + L. s | 13 | 0 | 1/3 | 0 |
| 9 | ||||
| 30 | 0 | 1/2 | 0 | |
| 10 | ||||
| L. s | 13 | 0 | 0 | 0 |
| 30 | 0 | 0 | 0 | |
The different groups of mice are listed in column 1. Time of necropsies is indicated in the second column. For both types of lesions observed in the kidneys, the ratio of mice with lesions to the total number of mice studied is indicated, as well as the mean number of glomeruli showing the lesions. D.p.i.: Day post-inoculation; prolif. proliferation; uninf: uninfected mice; L. s: mice infected by L. sigmodontis; P. y: mice infected by P. yoelii; P. y + L. s: mice co-infected by L. sigmodontis and P. yoelii; P. c: mice infected by P. chabaudi; P. c + L. s: mice co-infected by L. sigmodontis and P. chabaudi.
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