Open Access

Table 1.

Constitution of the three groups.

Group Investigational material Total dose volume Route Treatment Day Total No. animals
1 Untreated NA NA 6
2 FRONTLINE® Plus Based on dog’s weight, pipettes S or M
(respectively 0.67 or 1.34 mL),
Based on label recommendation
Topical Day 0 and Day 28 6
3 Physiological Oat meal extract shampoo Shampoo based on manufacturer recommendation Topical Days 0, 7, 14, 21, 28, 35, 42 and 53 6

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